Born in New York City, Luce moved around the United States (and France) with her mother, a professional dancer. She worked in acting, editing, and writing. Her second marriage, in 1935, was to Henry Luce, the publisher of Time and other major magazines. Beginning in 1942, she served two terms as a Representative from Connecticut in the U.S. House, and she later was ambassador to Italy. In 1946, influenced by Abp. Fulton Sheen, she entered the Catholic Church.